Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK13 All Species: 10.61
Human Site: S448 Identified Species: 25.93
UniProt: Q14004 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14004 NP_003709.3 1512 164923 S448 S T L T L K S S L A A E L N K
Chimpanzee Pan troglodytes XP_001139939 1512 164915 S448 S T L T L K S S L A A E L N K
Rhesus Macaque Macaca mulatta XP_001088594 1490 164086 S440 S S V E A K D S G L E S K K L
Dog Lupus familis XP_533082 1377 150158 D401 S G G T L K N D K A K T K P P
Cat Felis silvestris
Mouse Mus musculus Q69ZA1 1511 164590 S449 S T L T L K S S L A A E L N K
Rat Rattus norvegicus Q3MJK5 1484 163772 P423 G K E S K G S P I I L P K K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425866 1032 115177 A85 D T F S D D V A L K L D R R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687417 1286 141523 G339 T R R P V K S G S R S P Y P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46551 730 82410
Sea Urchin Strong. purpuratus XP_789337 1264 139419 K314 E P V P E P V K V K Q V K Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.4 82.5 N.A. 95.1 41.6 N.A. N.A. 29.7 N.A. 44 N.A. N.A. N.A. 24.6 32.6
Protein Similarity: 100 99.8 53.5 84.5 N.A. 96.8 53.9 N.A. N.A. 37.9 N.A. 55 N.A. N.A. N.A. 33.3 46.9
P-Site Identity: 100 100 20 33.3 N.A. 100 6.6 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 33.3 40 N.A. 100 26.6 N.A. N.A. 40 N.A. 33.3 N.A. N.A. N.A. 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 40 30 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 10 10 10 0 0 0 10 0 0 0 % D
% Glu: 10 0 10 10 10 0 0 0 0 0 10 30 0 0 20 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 0 0 10 0 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 0 10 0 0 10 60 0 10 10 20 10 0 40 20 30 % K
% Leu: 0 0 30 0 40 0 0 0 40 10 20 0 30 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 30 0 % N
% Pro: 0 10 0 20 0 10 0 10 0 0 0 20 0 20 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % Q
% Arg: 0 10 10 0 0 0 0 0 0 10 0 0 10 10 0 % R
% Ser: 50 10 0 20 0 0 50 40 10 0 10 10 0 0 10 % S
% Thr: 10 40 0 40 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 20 0 10 0 20 0 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _